NAFLD—which patients should have hepatocellular carcinoma surveillance?

Surveillance for Hepatocellular Carcinoma in Patients with NASH

European and American guidelines recommend surveillance for hepatocellular carcinoma (HCC) by performing ultrasonography on a six-month basis on an at risk population, defined by presence of cirrhosis. HCC, due to non-alcoholic steatohepatitis (NASH), is rising. Patients with NASH have a high risk of developing HCC and, therefore, have to be enrolled in a screening program. One of the challenge...

Effectiveness of hepatocellular carcinoma surveillance in patients with cirrhosis.

BACKGROUND Surveillance for hepatocellular carcinoma (HCC) is recommended in patients with cirrhosis, but the effectiveness of a surveillance program in clinical practice has yet to be established. AIMS To evaluate the effectiveness of a surveillance program with ultrasound and alpha-fetoprotein (AFP) to detect early HCCs. METHODS Four hundred and forty-six patients with Child A/B cirrhosis...

Hepatocellular Carcinoma in Sheep

Treatment of Stage IVA Hepatocellular Carcinoma Should

Main Outcome Measures: Intraoperative data, recurrence, and long-term survival rates were analyzed. Results: Postoperative mortality and morbidity were 5% and 30%, respectively. The median number of resected tumors per patient was 3, and the median diameter of the largest tumor was 60 mm. With a median follow-up of 23 months, 14 patients (70%) developed recurrence. Treatment of recurrence was p...

Surveillance and diagnosis for hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) is an important cause of cancer-related death worldwide. If the disease is detected early, the treatment is more likely to be curative. This article discusses the current evidence regarding the surveillance and diagnosis of HCC, focusing on recent articles and the recommendations of the American Association for the Study of Liver Diseases (AASLD), which are briefl...